I had personally participated in Oxford University's computer based cancer drug treatment research, which is currently going on via a worldwide peer to peer network of over 3,000,000 individual computers. The initial project screened 3.5 billion drug-like molecules against 12 Cancer targets. Several more targets were later added. Check here for semi-current news of this and related projects. I had been involved with this project since the end of May in 2001 and found it to be very worthwhile and pretty painless. We completed working on promising candidates for a treatment for Smallpox after infection on November 16, 2004. Currently there's no known treatment for Smallpox in that state. We also completed the ROSETTA Human Proteome Folding Project, which determines how proteins, coded by the human gene sequences, are most likely to fold. The knowledge gained will help scientists build the required understanding for the development of new treatments for diseases. On Friday, April 27, 2007, Grid.org announced it had completed its mission to demonstrate the viability and benefits of large-scale Internet-based grid computing, and retired its efforts to support critical health research. There are quite a number of other worthwhile health related research efforts to help out with. I chose the well known Folding@Home project, hosted by Stanford University. It is currently working on research projects for Alzheimer's Disease (my Mom (age 80) passed away in September 2001 from complications of this disease.); Cancer (I've lost count to how many people I've known over the years who have succumbed to various forms of this disease.);Huntington's Disease; Osteogenesis Imperfecta; Parkinson's Disease; Ribosome & antibiotics. If English is not your native language, they also have their web pages translated into Chinese, Dutch, French, German, Italian, Japanese, Korean, Persian, Polish, Portuguese, Russian, Spanish, and Vietnamese.